Evaluation of ligase chain reaction for the non-cultural detection of rectal and pharyngeal gonorrhoea in men who have sex with men.

@article{Young2003EvaluationOL,
  title={Evaluation of ligase chain reaction for the non-cultural detection of rectal and pharyngeal gonorrhoea in men who have sex with men.},
  author={Hugh Young and Kaveh Manavi and Alexander Mcmillan},
  journal={Sexually transmitted infections},
  year={2003},
  volume={79 6},
  pages={
          484-6
        }
}
OBJECTIVES To compare a nucleic acid amplification test (ligase chain reaction) with culture for detecting rectal and pharyngeal gonorrhoea in men who have sex with men (MSM). METHODS Duplicate rectal and throat swabs from MSM attending a genitourinary medicine clinic were collected for culture on modified New York City medium and detection of gonococcal nucleic acid by the Abbott ligase chain reaction (LCR) utilising probes based on opa 1 gene sequences. LCR positive culture negative… CONTINUE READING

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