Evaluation of intermolecular interactions of self-etch dentin adhesive primer molecules with type 1 collagen: computer modeling and in vitro binding analysis.

@article{Vaidyanathan2007EvaluationOI,
  title={Evaluation of intermolecular interactions of self-etch dentin adhesive primer molecules with type 1 collagen: computer modeling and in vitro binding analysis.},
  author={Jayalakshmi Vaidyanathan and Tritala K Vaidyanathan and John E. Kerrigan},
  journal={Acta biomaterialia},
  year={2007},
  volume={3 5},
  pages={
          705-14
        }
}
The objective of this investigation was to study adhesion of self-etch primer systems to dentin by computer-modeled docking simulations and in vitro binding assay methods. Computer modeling employed analysis of docking simulations of a self-etch primer molecule 10-methacryloxydecamethylene phosphoric acid (MDP) and its calcium salt (MDPCa) as ligands. Typical type 1 collagen segments were selected as targets to reflect potential differences in the amino acid residues in dentinal type 1 collagen… Expand
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Chemical affinity of 10-methacryloyloxydecyl dihydrogen phosphate to dental zirconia: Effects of molecular structure and solvents.
  • Ying Chen, Z. Lu, +4 authors F. Tay
  • Chemistry, Medicine
  • Dental materials : official publication of the Academy of Dental Materials
  • 2017
TLDR
It is indicated that solvent is necessary for the formation of Zr-O-P bonds between 10-MDP and Y-TZP; acetone facilitated the best bonding, followed by ethanol. Expand
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