Evaluation of insulin resistance in acromegalic patients before and after treatment with somatostatin analogues.

@article{Ronchi2003EvaluationOI,
  title={Evaluation of insulin resistance in acromegalic patients before and after treatment with somatostatin analogues.},
  author={Cristina L Ronchi and Emanuela Orsi and C Giavoli and Vincenzo Cappiello and Paolo Epaminonda and Paolo Beck-Peccoz and Maura Arosio},
  journal={Journal of endocrinological investigation},
  year={2003},
  volume={26 6},
  pages={533-8}
}
Many studies have recently shown that simple computer-solved indices, based on fasting glucose and insulin levels, closely mirror the euglycemic clamp technique in studying insulin resistance or pancreatic insulin secretion. Few data are at present available on the evaluation of these novel indices in acromegalic patients, known to be GH-dependent insulin-resistant subjects, in particular during medical treatment with somatostatin analogues. Indeed, these drugs are able to inhibit not only GH… CONTINUE READING

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