Evaluation of inflammation-related genes polymorphisms in Mexican with Alzheimer’s disease: a pilot study

@inproceedings{ToralRios2015EvaluationOI,
  title={Evaluation of inflammation-related genes polymorphisms in Mexican with Alzheimer’s disease: a pilot study},
  author={Danira Toral-Rios and Diana Franco-Bocanegra and Oscar Rosas-Carrasco and Francisco Mena-Barranco and Rosa Carvajal-Garc{\'i}a and Marco A Meraz-R{\'i}os and Victoria Campos-Pe{\~n}a},
  booktitle={Front. Cell. Neurosci.},
  year={2015}
}
Amyloid peptide is able to promote the activation of microglia and astrocytes in Alzheimer's disease (AD), and this stimulates the production of pro-inflammatory cytokines. Inflammation contributes to the process of neurodegeneration and therefore is a key factor in the development of AD. Some of the most important proteins involved in AD inflammation are: clusterin (CLU), complement receptor 1 (CR1), C reactive protein (CRP), tumor necrosis factor α (TNF-α), the interleukins 1α (IL-1α), 6 (IL… CONTINUE READING
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