Evaluation of in vitro vs. in vivo methods for assessment of dermal absorption of organic flame retardants: a review.

@article{Abdallah2015EvaluationOI,
  title={Evaluation of in vitro vs. in vivo methods for assessment of dermal absorption of organic flame retardants: a review.},
  author={Mohamed Abou-Elwafa Abdallah and Gopal V Pawar and Stuart J Harrad},
  journal={Environment international},
  year={2015},
  volume={74},
  pages={13-22}
}
There is a growing interest to study human dermal exposure to a large number of chemicals, whether in the indoor or outdoor environment. Such studies are essential to predict the systemic exposure to xenobiotic chemicals for risk assessment purposes and to comply with various regulatory guidelines. However, very little is currently known about human dermal exposure to persistent organic pollutants. While recent pharmacokinetic studies have highlighted the importance of dermal contact as a… CONTINUE READING

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