Evaluation of impact of statin use on development of CPK elevation during daptomycin therapy.

BACKGROUND Because both daptomycin and statins may increase creatine phosphokinase (CPK) levels, the manufacturer of daptomycin suggests considering holding statins during daptomycin therapy. Published evidence suggests potential detrimental effects of withdrawing statin therapy. OBJECTIVES The objectives of this study were to determine the impact of… CONTINUE READING