Evaluation of immune responses following infection of ponies with an EHV-1 ORF1/2 deletion mutant

@inproceedings{Hussey2011EvaluationOI,
  title={Evaluation of immune responses following infection of ponies with an EHV-1 ORF1/2 deletion mutant},
  author={Gisela Soboll Hussey and Stephen B Hussey and Bettina Wagner and David W. Horohov and Gerlinde R. Van de Walle and Nikolaus Osterrieder and Lutz S. Goehring and Sangeeta Rao and David P. Lunn},
  booktitle={Veterinary research},
  year={2011}
}
Equine herpesvirus-1 (EHV-1) infection remains a significant problem despite the widespread use of vaccines. The inability to generate a protective immune response to EHV-1 vaccination or infection is thought to be due to immunomodulatory properties of the virus, and the ORF1 and ORF2 gene products have been hypothesized as potential candidates with immunoregulatory properties. A pony infection study was performed to define immune responses to EHV-1, and to determine if an EHV-1 ORF1/2 deletion… CONTINUE READING
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elicits protective immune responses against EHV - 1 and H 3 N 8 equine influenza virus

  • LB Goodman, B Wagner, +4 authors N Osterrieder
  • 2010

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