Evaluation of humoral and cellular immune responses to BP26 and OMP31 epitopes in the attenuated Brucella melitensis vaccinated sheep.

@article{Wang2014EvaluationOH,
  title={Evaluation of humoral and cellular immune responses to BP26 and OMP31 epitopes in the attenuated Brucella melitensis vaccinated sheep.},
  author={Wenjing Wang and Jingbo Wu and Jun Qing Qiao and Yunceng Weng and Hui Zhang and Qingyu Liao and Jinlang Qiu and Chuangfu Chen and J-P Allain and Chengyao Li},
  journal={Vaccine},
  year={2014},
  volume={32 7},
  pages={825-33}
}
In recent years, the number of cases of human brucellosis has been increasing by approximately 10% per year in China. Most cases were caused by Brucella melitensis through contacts with infected sheep, goats or their products. An attenuated B. melitensis vaccine M5-90 is currently used to vaccinate both animals in China. This vaccine has not been investigated for critical parameters such as immune response and its association with protective efficacy. In this study, humoral and cellular immune… CONTINUE READING
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