Evaluation of high-protein supplementation in weight-stable HIV-positive subjects with a history of weight loss: a randomized, double-blind, multicenter trial.

@article{Sattler2008EvaluationOH,
  title={Evaluation of high-protein supplementation in weight-stable HIV-positive subjects with a history of weight loss: a randomized, double-blind, multicenter trial.},
  author={Fred R. Sattler and Natasa Rajicic and Kathleen Mulligan and Kevin E Yarasheski and Susan L. Koletar and Andrew Zolopa and Beverly Alston Smith and Robert A Zackin and Bruce Ryan Bistrian},
  journal={The American journal of clinical nutrition},
  year={2008},
  volume={88 5},
  pages={1313-21}
}
BACKGROUND HIV patients with wasting are at increased risk of opportunistic complications and fatality. OBJECTIVE We hypothesized that augmenting dietary intake with high-biologic-value protein would enhance weight and lean tissue in weight-stable subjects with a prior unintentional weight loss of >3%. DESIGN Fifty-nine subjects with HIV RNA concentrations <5000 copies/mL were randomly assigned to receive a 280-kcal supplement containing 40 g whey protein or a matched isocaloric control… CONTINUE READING

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