Evaluation of heterogeneity in pharmacotherapy trials for drug dependence: a Bayesian approach.

@article{Green2009EvaluationOH,
  title={Evaluation of heterogeneity in pharmacotherapy trials for drug dependence: a Bayesian approach.},
  author={Charles A. Green and F. Gerard Moeller and Joy M. Schmitz and Joseph F. Lucke and Scott D. Lane and Alan C. Swann and Robert E. Lasky and Joseph P Carbonari},
  journal={The American journal of drug and alcohol abuse},
  year={2009},
  volume={35 2},
  pages={95-102}
}
AIMS Difficulty identifying effective pharmacotherapies for cocaine dependence has led to suggestions that subgroup differences may account for some of the heterogeneity in treatment response. Well-attested methodological difficulties associated with these analyses recommend the use of Bayesian statistical reasoning for evaluation of salient interaction effects. METHODS A secondary data analysis of a previously published, double-blind, randomized controlled trial examines the interaction of… CONTINUE READING