Evaluation of halobetasol propionate ointment in the treatment of plaque psoriasis: report on two double-blind, vehicle-controlled studies.

@article{Bernhard1991EvaluationOH,
  title={Evaluation of halobetasol propionate ointment in the treatment of plaque psoriasis: report on two double-blind, vehicle-controlled studies.},
  author={Jeffrey D. Bernhard and Colin Whitmore and C. Guzzo and Irwin Kantor and Robert E. Kalb and C D Ellis and Frederick Urbach and E H Schwartzel and John R Gibson},
  journal={Journal of the American Academy of Dermatology},
  year={1991},
  volume={25 6 Pt 2},
  pages={1170-4}
}
The results of two studies are presented that reveal the efficacy and safety of 0.05% halobetasol ointment in the treatment of patients with plaque psoriasis of at least moderate severity. Both multicenter studies were randomized, double-blind, and vehicle controlled, and study medications were applied twice daily for 2 weeks. One study was a paired-comparison (PC); the other study was of parallel-group (PG) design. Both studies called for evaluations at entry (week 0) and after 1 and 2 weeks… CONTINUE READING

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