Evaluation of gonadal function in 107 intersex patients by means of serum antimüllerian hormone measurement.

  title={Evaluation of gonadal function in 107 intersex patients by means of serum antim{\"u}llerian hormone measurement.},
  author={Rodolfo Alberto Rey and Corinne Belville and Claire Nihoul-F{\'e}k{\'e}t{\'e} and Laurence Michel-Calemard and Maguelone G. Forest and Najiba Lahlou and Francis Jaubert and Ir{\`e}ne Mowszowicz and Michel David and Nurçin Saka and Claire Bouvattier and Anne Marie Bertrand and Claudine Lecointre and Sylvie Soskin and Sylvie Cabrol and H{\'e}l{\`e}ne Crosnier and Juliane L{\'e}ger and St{\'e}phen Lortat-Jacob and Marc Nicolino and Wolfgang Rabl and S{\'e}rgio Pereira de Almeida Toledo and Firdevs Baş and Anne Gompel and Paul C Czernichow and Nathalie Josso},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={84 2},
Fetal male sexual differentiation is driven by two testicular hormones: testosterone (synthesized by interstitial Leydig cells) and antimüllerian hormone (AMH; produced by Sertoli cells present in the seminiferous tubules). Intersex states result either from gonadal dysgenesis, in which both Leydig and Sertoli cell populations are affected, or from impaired secretion or action of either testosterone or AMH. Until now, only Leydig cell function has been assessed in children with ambiguous… CONTINUE READING


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