Evaluation of glycomic profiling as a diagnostic biomarker for epithelial ovarian cancer.

@article{Kim2014EvaluationOG,
  title={Evaluation of glycomic profiling as a diagnostic biomarker for epithelial ovarian cancer.},
  author={Kyoungmi Kim and L. Renee Ruhaak and Uyen Thao Nguyen and Sandra L. Taylor and Lauren M Dimapasoc and Cynthia Williams and Carol D Stroble and Sureyya Ozcan and Suzanne Miyamoto and Carlito B. Lebrilla and Gary S. Leiserowitz},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2014},
  volume={23 4},
  pages={
          611-21
        }
}
BACKGROUND Prior studies suggested that glycans were differentially expressed in patients with ovarian cancer and controls. We hypothesized that glycan-based biomarkers might serve as a diagnostic test for ovarian cancer and evaluated the ability of glycans to distinguish ovarian cancer cases from matched controls. METHODS Serum samples were obtained from the tissue-banking repository of the Gynecologic Oncology Group, and included healthy female controls (n = 100), women diagnosed with low… CONTINUE READING

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