Evaluation of glutathione S-transferase P1 genetic variants affecting type-2 diabetes susceptibility and glycemic control

@inproceedings{Amer2012EvaluationOG,
  title={Evaluation of glutathione S-transferase P1 genetic variants affecting type-2 diabetes susceptibility and glycemic control},
  author={Mahmoud A. Amer and Maivel H. Ghattas and Dina M. Abo-elmatty and Soad H. Abou-El-Ela},
  booktitle={Archives of medical science : AMS},
  year={2012}
}
INTRODUCTION Type 2 diabetes mellitus (T2DM) is associated with increased production of reactive oxygen species and a reduction in antioxidant defenses leading to oxidative stress. Glutathione S-transferases (GSTs) modulate oxidative stress. The present cross-sectional study was aimed at investigating the association between the GSTP1 gene polymorphism and T2DM and to clarify their effect on the glycemic control parameters. MATERIAL AND METHODS From the Egyptian population, we enrolled 112… CONTINUE READING

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