Evaluation of genotoxic effects in a group of workers exposed to low levels of styrene.

@article{Laffon2002EvaluationOG,
  title={Evaluation of genotoxic effects in a group of workers exposed to low levels of styrene.},
  author={Blanca Laffon and Eduardo P{\'a}saro and Josefina M{\'e}ndez},
  journal={Toxicology},
  year={2002},
  volume={171 2-3},
  pages={175-86}
}
Occupational exposure to styrene was studied in a group of workers engaged in the production of fiberglass-reinforced plastics. Sister-chromatid exchanges (SCE), micronuclei (MN), and DNA damage (evaluated by means of comet assay) were measured in peripheral blood cells from the exposed workers and from a control population. Mandelic acid concentration, an indicator of styrene exposure level, was measured in urine samples collected at the end of the work shift. Average estimated values for… CONTINUE READING