Evaluation of genome-wide association study-identified type 2 diabetes loci in African Americans.

@article{Long2012EvaluationOG,
  title={Evaluation of genome-wide association study-identified type 2 diabetes loci in African Americans.},
  author={Jirong Long and Todd D Edwards and Lisa B. Signorello and Qiuyin Cai and Wei Zheng and Xiao-ou Shu and William J. Blot},
  journal={American journal of epidemiology},
  year={2012},
  volume={176 11},
  pages={995-1001}
}
Type 2 diabetes (T2D) is up to twice as prevalent among African Americans as Caucasians. Recent genome-wide association studies (GWAS) have identified multiple common genetic risk variants for T2D; however, none of these studies were conducted exclusively among subjects of African ancestry. Investigating these known loci in other populations would be an expedient way to evaluate the generalizability of the current findings. The authors evaluated 29 known T2D loci in a large southeastern US… CONTINUE READING
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