Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis.

Abstract

OBJECTIVES Combination therapy that includes fusidic acid, an antimicrobial agent highly active against staphylococci, has been recommended in the treatment of patients with Staphylococcus aureus meningitis. The aim of this study was to evaluate the pharmacokinetic, CSF bactericidal and anti-inflammatory properties of fusidic acid. METHODS The… (More)

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