Evaluation of four automated methods for determination of whole blood cyclosporine concentrations.

@article{Hamwi1999EvaluationOF,
  title={Evaluation of four automated methods for determination of whole blood cyclosporine concentrations.},
  author={Ahmad Hamwi and Mario Veitl and Georg Maenner and Katharina Ruzicka and Christoph Schweiger and Th. Szekeres},
  journal={American journal of clinical pathology},
  year={1999},
  volume={112 3},
  pages={
          358-65
        }
}
Cyclosporine is a widely used and potent immunosuppressant drug with a narrow therapeutic index. Therefore, cyclosporine concentrations should be monitored closely. Various automated immunologic methods for cyclosporine whole blood determinations are available. Two new methods, fluorescence polarization immunoassay (FPIA) for the AxSYM by Abbott Laboratories, Chicago, IL, and the cloned enzyme donor immunoassay (CEDIA) by Boehringer Mannheim, Mannheim, Germany, have been introduced. In addition… CONTINUE READING
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