Corpus ID: 37301475

Evaluation of fluorinated m-tyrosine analogs as PET imaging agents of dopamine nerve terminals: comparison with 6-fluoroDOPA.

@article{DeJesus1997EvaluationOF,
  title={Evaluation of fluorinated m-tyrosine analogs as PET imaging agents of dopamine nerve terminals: comparison with 6-fluoroDOPA.},
  author={O. DeJesus and C. Endres and S. Shelton and R. Nickles and J. Holden},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1997},
  volume={38 4},
  pages={
          630-6
        }
}
  • O. DeJesus, C. Endres, +2 authors J. Holden
  • Published 1997
  • Chemistry, Medicine
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine
UNLABELLED Fluorinated m-tyrosine analogs were evaluated as PET imaging agents and compared with 6-fluoroDOPA in the visualization of dopamine nerve terminals. METHODS The three m-tyrosine analogs, 6-[18F]fluoro-L-m-tyrosine (6-FMT), 2-[18F]fluoro-L-m-tyrosine (2-FMT) and 6-[18F]fluoro-fluoromethylene-DL-m-tyrosine (6-F-FMMT), were prepared via electrophilic radiofluorination using [18F]acetylhypofluorite. These three analogs, as well as 6-[18F]fluoro-L-DOPA (6-FD), were injected into sets of… Expand
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