Evaluation of femoral perfusion in a non-traumatic rabbit osteonecrosis model with T2*-weighted dynamic MRI.

@article{Tsuji2003EvaluationOF,
  title={Evaluation of femoral perfusion in a non-traumatic rabbit osteonecrosis model with T2*-weighted dynamic MRI.},
  author={Takashi Tsuji and Nobuhiko Sugano and Takashi Sakai and Hideki Yoshikawa},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2003},
  volume={21 2},
  pages={341-51}
}
We evaluated femoral perfusion in a non-traumatic rabbit serum sickness osteonecrosis (ON) model, using serial repetitive T2*-weighted (T2*W) dynamic magnetic resonance imaging (MRI) and investigated prediction of ON occurrence in early stages, comparing T2*W dynamic MRI with non-enhanced (T2-, T1- and fat suppression T1-weighted) and contrast-enhanced MRI. Early microcirculatory injury or necrotic lesion was detected in 0% of femora (extravasation, 0/6) at 72 h, 33% (necrotic, 4/12) at 1 week… CONTINUE READING