Evaluation of exhaled breath condensate pH as a biomarker for COPD.

  title={Evaluation of exhaled breath condensate pH as a biomarker for COPD.},
  author={W. MacNee and Stephen I. Rennard and John Francis Hunt and Lisa D. Edwards and Bruce E. Miller and Nicholas W Locantore and Ruth Tal-Singer},
  journal={Respiratory medicine},
  volume={105 7},
INTRODUCTION We assessed the utility of EBC pH as a biomarker in COPD in a large cohort of well-characterised individuals with COPD and control subjects from the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study. We also determined short term reproducibility and the response of EBC to oral prednisolone. METHODS EBC was collected with R-Tubes(TM), using techniques for sampling and measurement that have been shown to be reproducible. RESULTS EBC pH… CONTINUE READING


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