Evaluation of efflux pump gene expression among drug susceptible and drug resistant strains of Mycobacterium tuberculosis from Iran.

@article{Yamchi2015EvaluationOE,
  title={Evaluation of efflux pump gene expression among drug susceptible and drug resistant strains of Mycobacterium tuberculosis from Iran.},
  author={Jalil Kardan Yamchi and Mehri Haeili and Seifu Gizaw Feyisa and Hossein Kazemian and Abdolrazagh Hashemi Shahraki and Fatemeh Zahednamazi and Abbas Ali Imani Fooladi and Mohammad Mehdi Feizabadi},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2015},
  volume={36},
  pages={23-26}
}
Absence of mutations within the genes encoding drug targets in some phenotypically drug resistant strains of Mycobacterium tuberculosis suggests possible involvement of alternative mechanisms such as over-expression of efflux pumps. We investigated the expression level of Rv1410c, Rv2459, Rv1218c and Rv1273c efflux pumps gene by real-time quantitative… CONTINUE READING