Evaluation of effective renal plasma flow with I-127 ortho-iodohippurate and I-123 ortho-iodohippurate in rabbits.

  title={Evaluation of effective renal plasma flow with I-127 ortho-iodohippurate and I-123 ortho-iodohippurate in rabbits.},
  author={G Mariani and Carla Augeri and Fabio Pretolesi and Eugenio Mereto and Giovanna Curti and Carlo Martinoli and Antonietta Martelli and Lorenzo E. Derchi},
  journal={Academic radiology},
  volume={7 9},
RATIONALE AND OBJECTIVES Radiolabeled ortho-iodohippurate is commonly employed for evaluating effective renal plasma flow (ERPF) by means of either in vivo scintigraphy and/or plasma clearance curves. A new method has recently been developed for measuring levels of stable iodine (iodine-127) in biologic samples, based on the detection of x-ray fluorescence photons. In this study, the authors assessed the potential of the new system to evaluate ERPF by using an iodinated contrast medium with… Expand
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The liver and kidneys perform vital functions in the body and their numerous roles expose them to various forms of toxic materials and events. To prevent these organ failures, much effort has beenExpand


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  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine
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HPLC purified MAG3 behaved similarly to OIH under adverse physiologic conditions and the data continue to support the use of MAG3 as a potential clinical substitute for OIh. Expand
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Glomerular filtration rate can be reliably determined with a low dose of iohexol and a single blood sample obtained three hours after the injection in persons with normal serum creatinine, and is a good alternative to the methods using radiopharmaceuticals. Expand
Quantitation of renal function with glomerular and tubular agents.
Estimation of ERPF with radioiodinated OIH and GFR with 99mTcDTPA can be achieved in many ways, all of which yield clinically useful results, and the preference at the present time is to use a single or double plasma sample to calculate global ERPF or GFR. Expand
The effect of intravenous contrast medium on glomerular filtration rate.
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  • Medicine
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  • 1984
It is suggested that an important factor in the decrease in GFR is the rise in pressure in the renal tubules at the start of a diuresis, before they have had time to dilate. Expand
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Accuracy and reproducibility of a new contrast clearance method for the determination of glomerular filtration rate.
A new method using an x ray fluorescence technique to measure disappearance from the plasma of injected non-ionic iodinated contrast media merits further study and might find a useful place in routine clinical practice. Expand
Measurement of the plasma clearance of urographic contrast media for the determination of glomerular filtration rate.
The contrast clearance technique for the measurement of glomerular filtration rate during excretory urography is simple, quick and accurate, and merits further development. Expand