Evaluation of drugs for treatment of prion infections of the central nervous system.

Abstract

Prion diseases are fatal and at present there are neither cures nor therapies available to delay disease onset or progression in humans. Inspired in part by therapeutic approaches in the fields of Alzheimer's disease and amyotrophic lateral sclerosis, we tested five different drugs, which are known to efficiently pass through the blood-brain barrier, in a… (More)
DOI: 10.1099/vir.0.83281-0

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