Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti

@inproceedings{Carter2012EvaluationOD,
  title={Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti},
  author={Tamar E. Carter and Megan Warner and Connie J. Mulligan and Alexandre Existe and Yves Saint Victor and Gladys Memnon and Jacques Boncy and Roland Oscar and Mark M Fukuda and Bernard A. Okech},
  booktitle={Malaria Journal},
  year={2012}
}
Malaria caused by Plasmodium falciparum infects roughly 30,000 individuals in Haiti each year. Haiti has used chloroquine (CQ) as a first-line treatment for malaria for many years and as a result there are concerns that malaria parasites may develop resistance to CQ over time. Therefore it is important to prepare for alternative malaria treatment options should CQ resistance develop. In many other malaria-endemic regions, antifolates, particularly pyrimethamine (PYR) and sulphadoxine (SDX… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Team: A Language and Environment for Statistical Computing

R Development Cor
2141st edition. Vienna, Austria: R Foundation for Statistical Computing; • 2011

Stepwise acquisition of pyrimethamine resistance in the malaria parasite.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 2 Excerpts

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