Evaluation of diagnostic methods for Helicobacter bilis infection in laboratory mice.

@article{Hodzic2001EvaluationOD,
  title={Evaluation of diagnostic methods for Helicobacter bilis infection in laboratory mice.},
  author={Emir Hodzic and Maureen D. McKisic and Sunlian Feng and Stephen W. Barthold},
  journal={Comparative medicine},
  year={2001},
  volume={51 5},
  pages={406-12}
}
Disease-susceptible (C3H) and -resistant (B6) immunocompetent and immunodeficient (C3H-scid and B6-rag1) mice were examined up to 10 weeks after inoculation with Helicobacter bilis (a prototype species of proven virulence). Infection was monitored weekly by use of fecal culture, polymerase chain reaction (PCR) nucleic acid amplification, membrane extract enzyme-linked immunosorbent assay (ELISA), and histologic examination. All mice became infected by three to five weeks after inoculation, on… CONTINUE READING