Evaluation of deuterated cholesterol and deuterated sitostanol for measurement of cholesterol absorption in humans.

@article{Ltjohann1993EvaluationOD,
  title={Evaluation of deuterated cholesterol and deuterated sitostanol for measurement of cholesterol absorption in humans.},
  author={Dieter L{\"u}tjohann and C. O. Meese and John Robert Crouse and Klaus von Bergmann},
  journal={Journal of lipid research},
  year={1993},
  volume={34 6},
  pages={1039-46}
}
The continuous isotope feeding method of Crouse and Grundy (1978. J. Lipid Res. 19: 967-971) for measurement of dietary cholesterol absorption has been modified by using markers labeled with stable isotopes ([2,2,4,4,6-2H5]cholesterol or [25,26,26,26,27,27,27-2H4]cholesterol or [26,26,26,27,27,27-2H6] cholesterol and [5,6,22,23-2H4]sitostanol) quantified by gas-liquid chromatography-selected ion monitoring. Tracing of the isotope distribution of the authentic markers and after their intestinal… CONTINUE READING