Evaluation of cytotoxicity of different tobacco product preparations.

  title={Evaluation of cytotoxicity of different tobacco product preparations.},
  author={Subhashini Arimilli and Brad E Damratoski and Betsy R Bombick and Michael F. Borgerding and Gaddamanugu L. Prasad},
  journal={Regulatory toxicology and pharmacology : RTP},
  volume={64 3},
Acute exposure to cigarette smoke or its components triggers diverse cellular effects, including cytotoxicity. However, available data regarding the potential cytotoxic effects of smokeless tobacco (ST) extracts lack consensus. Here, we investigated the relative biological effects of 2S3 reference ST, and whether ST elicits differential cellular/molecular responses compared to combustible tobacco product preparations (TPPs) prepared from 3R4F cigarettes. Total particulate matter (TPM) and whole… CONTINUE READING


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