Corpus ID: 13060745

Evaluation of cytotoxicity and antiviral activity of ivermectin against Newcastle disease virus.

@article{Azeem2015EvaluationOC,
  title={Evaluation of cytotoxicity and antiviral activity of ivermectin against Newcastle disease virus.},
  author={S. Azeem and M. Ashraf and M. A. Rasheed and A. Anjum and R. Hameed},
  journal={Pakistan journal of pharmaceutical sciences},
  year={2015},
  volume={28 2},
  pages={
          597-602
        }
}
Cytotoxic and antiviral potential of ivermectin and ribavirin was evaluated. Cytotoxicity was checked on chick primary fibroblast cell line through MTT assay. Antiviral potential was determined against Newcastle disease virus on 9-day old chicken embryos. Six different concentrations (200, 100, 50, 25, 12.5 and 6.25μg/ml) of both the drugs were evaluated. The 100μg/ml concentration of ivermectin and higher were cytotoxic. The 25μg/ml concentration of ribavirin and higher were cytotoxic… Expand
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