Evaluation of conserved and variable influenza antigens for immunization against different isolates of H5N1 viruses.

@article{Patel2009EvaluationOC,
  title={Evaluation of conserved and variable influenza antigens for immunization against different isolates of H5N1 viruses.},
  author={Ami J Patel and Kaylie N. Tran and Michael T. Gray and Yan Li and Zhujun Ao and Xiao-jian Yao and Darwyn Kobasa and Gary P Kobinger},
  journal={Vaccine},
  year={2009},
  volume={27 23},
  pages={3083-9}
}
The combination of rapid evolution and high mortality in human cases of infections has raised concerns that the H5N1 avian influenza virus may become a new, possibly severe, pandemic virus. Vaccination is likely to be the most efficient strategy to mitigate the impact of the next influenza pandemic. The present study evaluates B and T cell immune responses generated by the H5N1 viral antigens, hemagglutinin (HA), neuraminidase (NA), nucleoprotein (NP), or the M2 ion channel in parallel… CONTINUE READING

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