Evaluation of commercial assay detecting specific immunoglobulin g in oral fluid for determining measles immunity in vaccinees.

@article{Kremer2005EvaluationOC,
  title={Evaluation of commercial assay detecting specific immunoglobulin g in oral fluid for determining measles immunity in vaccinees.},
  author={Jacques R. Kremer and Claude P. Muller},
  journal={Clinical and diagnostic laboratory immunology},
  year={2005},
  volume={12 5},
  pages={668-70}
}
A commercial assay for detection of measles immunoglobulin G (IgG) in oral fluid was evaluated in a highly vaccinated cohort using serum IgG as gold standard. In contrast to previous studies from cohorts protected by natural immunity, antibody prevalence was significantly underestimated (-7.4%; confidence interval: -1.5 to -13.2%; P = 0.01) due to a reduced sensitivity when antibody levels were low. 

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