Evaluation of colonic sensory thresholds in IBS patients using a barostat

@article{Bradette1994EvaluationOC,
  title={Evaluation of colonic sensory thresholds in IBS patients using a barostat},
  author={Marc Bradette and PhD M. Delvaux and Ghislain Staumont and Jean Fioramonti DSc and Lionel Bueno DSc and Jacques Frexinos},
  journal={Digestive Diseases and Sciences},
  year={1994},
  volume={39},
  pages={449-457}
}
To study the role of abnormal visceral perception in the pathophysiology of the irritable bowel syndrome (IBS), we evaluated colonic tone and visceral perception during intracolonic distension using a flaccid balloon connected to a computerized barostat and placed in the descending colon of IBS patients and healthy controls. In the first part of the study, basal colonic tone and response to pharmacological (neostigmine and glucagon) and physiological (1000-kcal meal) stimuli were recorded in… CONTINUE READING