Evaluation of clonal origin of malignant mesothelioma

Abstract

The hypothesis that most cancers are of monoclonal origin is often accepted as a fact in the scientific community. This dogma arose decades ago, primarily from the study of hematopoietic malignancies and sarcomas, which originate as monoclonal tumors. The possible clonal origin of malignant mesothelioma (MM) has not been investigated. Asbestos inhalation… (More)
DOI: 10.1186/s12967-014-0301-3

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