• Corpus ID: 7015316

Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension.

  title={Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension.},
  author={Young-In Kwon and Dhiraj A. Vattem and Kalidas Shetty},
  journal={Asia Pacific journal of clinical nutrition},
  volume={15 1},
In the current study, we screened 7 clonal lines from single seed phenotypes of Lamiaceae family for the inhibition of alpha-amylase, alpha-glucosidase and angiotensin converting enzyme (ACE) inhibitory activity. Water extracts of oregano had the highest alpha-glucosidase inhibition activity (93.7%), followed by chocolate mint (85.9%) and lemon balm (83.9%). Sage (78.4 %), and three different clonal lines of rosemary: rosemary LA (71.4%), rosemary 6 (68.4%) and rosemary K-2 (67.8%) also showed… 
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The finding that clonal oregano extracts can inhibit PPA supports a potential new functionality for oregana as an anti-hyperglycemic agent and provides an opportunity for a food-based strategy for modulation of starch breakdown to glucose, which could contribute to the management of hyperglycemia and diabetes complications in the long term.
Biotechnology to harness the benefits of dietary phenolics; focus on Lamiaceae.
  • K. Shetty
  • Biology
    Asia Pacific journal of clinical nutrition
  • 1997
Long-term research objecitves of the food biotechnology program at the University of Massachusetts are to elucidate the molecular and physiological mechanisms associated with synthesis of important health-related, therapeutic phenolic metabolites in food-related plants and fermented plant foods.
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Taxonomic characteristics of strains NR-320-OM7HB and NR-320-OM7HBS producing a homologous series of new alpha-amylase inhibitors named trestatins are described, together with the comparison of these
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A novel tissue-culture-based selection strategy is developed to isolate elite phenolic phytochemical-producing clonal lines of species belonging to the family Lamiaceae that hold promise against a wide range of food pathogens such as Salmonella species in poultry products and Vibrio species in seafood.