Evaluation of circulating miRNAs in wet age-related macular degeneration

  title={Evaluation of circulating miRNAs in wet age-related macular degeneration},
  author={Sevda Ertekin and {\"O}zlem İlhan Yıldırım and Erdem Dinc and Lokman Ayaz and Şenay Balcı Fidancı and Lulufer Tamer},
  booktitle={Molecular vision},
PURPOSE In the present study, we aimed to investigate the changes in plasma miRNA in patients with wet age-related macular degeneration. METHODS The expression profiles of 384 miRNAs in plasma from 33 patients (22 male, 11 female) who were diagnosed with wet age-related macular degeneration with fundus examination, fundus fluorescein angiography, and optical coherence tomography and 31 controls (17 male, 14 female) were evaluated using high-throughput quantitative real-time PCR. RESULTS Our… CONTINUE READING