Evaluation of chromosome aberrations, sister chromatid exchange and micronuclei in patients with type-1 diabetes mellitus.

@article{Cinkilic2009EvaluationOC,
  title={Evaluation of chromosome aberrations, sister chromatid exchange and micronuclei in patients with type-1 diabetes mellitus.},
  author={Nil{\"u}fer Cinkilic and Sinem Kiyici and Serap Celikler and Ozgur Vatan and Ozen Oz Gul and Ercan Tuncel and Rahmi Bilaloğlu},
  journal={Mutation research},
  year={2009},
  volume={676 1-2},
  pages={
          1-4
        }
}
Oxidative stress-induced DNA damage seems to play a role in the pathogenesis of type-1 diabetes mellitus and its complications. Several in vitro assays have been used to measure the DNA damage produced by oxidative stress. In the present study, we aimed to investigate the frequency of sister chromatid exchange (SCE), chromosomal aberrations (CA) and micronuclei (MN) in type-1 diabetes mellitus patients compared with healthy controls. SCE, CA and MN tests were carried out with the blood-cell… CONTINUE READING

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