Evaluation of chikusetsusaponin IVa isolated from Alternanthera philoxeroides for its potency against viral replication.

@article{Rattanathongkom2009EvaluationOC,
  title={Evaluation of chikusetsusaponin IVa isolated from Alternanthera philoxeroides for its potency against viral replication.},
  author={A. Rattanathongkom and Jung-Bum Lee and K. Hayashi and B. Sripanidkulchai and T. Kanchanapoom and Toshimitsu Hayashi},
  journal={Planta medica},
  year={2009},
  volume={75 8},
  pages={
          829-35
        }
}
Chikusetsusaponin IVa and calenduloside E were isolated from the whole plant of Alternanthera philoxeroides (Mart.) Griseb (Amaranthaceae) and evaluated for their antiviral activities. Chikusetsusaponin IVa showed antiviral activities against HSV-1, HSV-2, human cytomegalovirus, measles virus, and mumps virus with selectivity indices (CC (50)/IC (50)) of 29, 30, 73, 25, and 25, respectively. On the other hand, calenduloside E showed no antiviral effects against any of the viruses tested. The… Expand
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