Evaluation of cartilage repair tissue after biomaterial implantation in rat patella by using T2 mapping

@article{WatrinPinzano2004EvaluationOC,
  title={Evaluation of cartilage repair tissue after biomaterial implantation in rat patella by using T2 mapping},
  author={Astrid Watrin-Pinzano and J.-P. Ruaud and Yann Cheli and Patrick Gonord and Laurent Grossin and Isabelle Bettembourg-Brault and Pierre Gillet and Elisabeth Payan and Genevi{\`e}ve Guillot and Patrick Netter and Damien Loeuille},
  journal={Magnetic Resonance Materials in Physics, Biology and Medicine},
  year={2004},
  volume={17},
  pages={219-228}
}
To evaluate the ability of MR T2 mapping (8.5 T) to characterize ex vivo longitudinally, morphologically and quantitatively, alginate-based tissue engineering in a rat model of patellar cartilage chondral focal defect. Calibrated rat patellar cartilage defects (1.3 mm) were created at day 0 (D0) and alginate sponge with (Sp/C+) or without (Sp/C−) autologous chondrocytes were implanted. Animals were sacrificed sequentially at D20, D40 and D60 after surgery and dissected patellae underwent MRI… CONTINUE READING
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