Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae isolates in the clinical laboratory.

@article{Tsakris2009EvaluationOB,
  title={Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae isolates in the clinical laboratory.},
  author={Athanassios Tsakris and Ioulia Kristo and Aggeliki Poulou and Katerina Themeli-Digalaki and Alexandros Ikonomidis and Dimitra Petropoulou and Spyros Pournaras and Danai Sofianou},
  journal={Journal of clinical microbiology},
  year={2009},
  volume={47 2},
  pages={362-7}
}
The worldwide increase in the occurrence and dissemination of KPC beta-lactamases among gram-negative pathogens makes critical the early detection of these enzymes. Boronic acid disk tests using different antibiotic substrates were evaluated for detection of KPC-possessing Klebsiella pneumoniae isolates. A total of 57 genotypically confirmed KPC-possessing K. pneumoniae isolates with varying carbapenem MICs were examined. To measure the specificity of the tests, 106 non-KPC-possessing isolates… CONTINUE READING