Evaluation of baroreceptor reflex function in the chronic mild stress rodent model of depression.

@article{Grippo2008EvaluationOB,
  title={Evaluation of baroreceptor reflex function in the chronic mild stress rodent model of depression.},
  author={Angela J. Grippo and Julia A Moffitt and Alan Kim Johnson},
  journal={Psychosomatic medicine},
  year={2008},
  volume={70 4},
  pages={435-43}
}
OBJECTIVE There is a bidirectional relationship between mood disorders (e.g., depression) and altered cardiovascular regulation (e.g., heart disease); however, the precise causal and/or common mechanisms underlying this association are unclear. In previous studies, we have noted indications of altered sympathetic drive to the heart in rats that exhibit anhedonia, an operational sign of depression induced by subjecting the animals to a series of mild and unpredictable stressors (chronic mild… CONTINUE READING

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