Evaluation of anxiolytic potential of Celastrus oil in rat models of behaviour.

Abstract

The Celastrus oil, extracted from seeds of Celastrus paniculatus tested at 2 dose levels (1 and 1.5 g/kg), exhibited significant anxiolytic activity and did not produce tolerance. The non-sedative nature and reversal of buspirone induced behaviour (in open field exploration) point to the serotonergic mechanism underlying the anxiolysis, inspiring further… (More)

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Cite this paper

@article{Rajkumar2007EvaluationOA, title={Evaluation of anxiolytic potential of Celastrus oil in rat models of behaviour.}, author={Ramamoorthy Rajkumar and Elavarasan Prem Kumar and Suresh Sudha and Bhojraj Suresh}, journal={Fitoterapia}, year={2007}, volume={78 2}, pages={120-4} }