Evaluation of anxiolytic activity of compound Valeriana jatamansi Jones in mice

  title={Evaluation of anxiolytic activity of compound Valeriana jatamansi Jones in mice},
  author={Jie-shu You and Min Peng and Jin-li Shi and Hu-zhan Zheng and Yong jin Liu and Bao-sheng Zhao and Jian-You Guo},
  booktitle={BMC complementary and alternative medicine},
BACKGROUND Compound Valeriana jatamansi Jones is a formula for treating anxiety-related diseases in the clinic, which is composed of Valeriana jatamansi Rhizoma et Radix, Ziziphi Spinosae Semen, Albiziae Cortex and Junci Medulla. The purpose of this study was to explore the anxiolytic properties of this compound in mice. METHODS Male ICR mice were treated with compound Valerianae Jatamansi Jones (1.2 g/kg, 2.4 g/kg, 4.8 g/kg), saline, diazepam (2 mg/kg) orally for 10 days and then exposed to… CONTINUE READING
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