Corpus ID: 4950297

Evaluation of antifungal effect of grape seed extract (GSE) on Candida glabrata and Candida krusei: in vitro study

  title={Evaluation of antifungal effect of grape seed extract (GSE) on Candida glabrata and Candida krusei: in vitro study},
  author={Hosein Eslami and Hossein Babaei and Solmaz Pourzare Mehrbani and Marzieh Aghazadeh and Zahra Babaei and Sahar Khadem Nezhad},
  journal={Biomedical Research-tokyo},
Background: Recently, following the widespread use of broad-spectrum antibiotics and immunosuppressive treatments, the prevalence of mucosal and systemic infections caused by glabrata and Candida krusei has been increased significantly. On the other hand, in addition to the problems caused by side effects of common antifungal drugs, the conducted studies have been indicative of the failure of antifungal treatments on Candidiasis different clinical infections and drug resistance including… Expand
5 Citations
Evaluation of the Antimicrobial Effect of the Extracts of the Pods of Piliostigma thonningii (Schumach.) Milne-Redh. (Fabaceae)
The pods of P. thonningii contain phytochemicals with antimicrobial properties, and the extract with the highest antimicrobial effects was ethanol extract, which caused significant leakage of proteins in these microorganisms. Expand
Antifungal Effects of Herbal Extracts and Fluconazole on Heat-polymerized Acrylic Denture Base Resin as Denture Cleanser: An In Vitro Study.
Results of this in vitro study showed that origanum oil was more effective than commercially available antifungal agents, and among the tested groups oregano oil was a potential agent in lowering the C. albicans colony. Expand
Antifungal Activity of Phenolic and Polyphenolic Compounds from Different Matrices of Vitis vinifera L. against Human Pathogens
This review summarizes studies that examine the extraction method, chemical characterization, and antifungal activity of phenolic and polyphenolic compounds from edible and non-edible V. vinifera matrices against human fungal pathogens. Expand
The Antimicrobial Activities of Silver Nanoparticles from Aqueous Extract of Grape Seeds against Pathogenic Bacteria and Fungi
The results showed significant antimicrobial activities of GSE-AgNPs against all tested species, unlike GSE, which had weaker and limited effects. Expand
An In Vitro Assessment of Surface Roughness, Tensile Bond Strength and Antifungal Activity of Grape Seed Extract-modified Soft Liner.
  • N. S. Aref
  • Medicine, Materials Science
  • The journal of contemporary dental practice
  • 2020
The GSE of 10% w/w considerably enhanced the antifungal activity and tensile bond strength of the modified soft liner to the denture base material without compromising its surface roughness. Expand


Synergic effect of grape seed extract with amphotericin B against disseminated candidiasis due to Candida albicans.
  • Yongmoon Han
  • Biology, Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
  • 2007
Results showed that the GSE alone inhibited growth of C. albicans yeast cells, and that in a murine model of disseminated candidiasis mice groups given GSE before intravenous inoculation with the yeast cells survived longer than diluent-received mice groups, implying that GSE has a synergic effect with Amp B. Expand
A Comparison of the eFficacy of Nystatin and Fluconazole Incorporated into Tissue Conditioner on the In Vitro Attachment and Colonization of Candida Albicans
Tissue conditioner with 1% to 10% nystatin or 10% fluconazole can completely inhibit the adhesion and colonization of Candida albicans. Expand
Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross‐resistance to triazole antifungal agents
The cross‐resistance to triazole among C. glabrata isolates was associated with previous fluconazole exposure as opposed to clonal spreading, and selection pressure due to flu Conazole use may play a major role in triazoles cross-resistance. Expand
Comparison of the antibacterial efficiency of neem leaf extracts, grape seed extracts and 3% sodium hypochlorite against E. feacalis - An in vitro study.
It was concluded that neem leaf extract has a significant antimicrobial effect against E. faecalis, which opens perspectives for its use as an intracanal medication. Expand
[Antifungal and fungicidal activities of tea extract and catechin against Trichophyton].
We examined tea extract, (-) epigallocatechin gallate (EGCg) and theaflavin digallate (TF3) for their antifungal and fungicidal activities against Trichophyton mentagrophytes, T. rubrum, CandidaExpand
Grape Seed Extract for Control of Human Enteric Viruses
The results indicate that GSE shows promise for application in the food industry as an inexpensive novel natural alternative to reduce viral contamination and enhance food safety. Expand
Well diffusion for antifungal susceptibility testing.
The well diffusion test is simple, easy to reproduce, inexpensive, easy both to read and interpret, and has a good correlation to the reference NCCLS microdilution test and may represent an alternative method for antifungal drug susceptibility testing of Candida spp. Expand
In vitro antimicrobial effects of grape seed extract on peri-implantitis microflora in craniofacial implants.
The results of the study showed that grape seed has potential antimicrobial effects which can be further studied and developed to be used in the treatment of infected skin-abutment interface of craniofacial implants. Expand
Grape seed extract inhibits the growth and pathogenicity of Staphylococcus aureus by interfering with dihydrofolate reductase activity and folate-mediated one-carbon metabolism.
GSE might serve as an effective natural alternative for the control of food poisoning caused by S. aureus with proper safety measure, indicated that GSE-induced perturbation in folate-mediated one-carbon metabolism has more profound impact on methionine cycle than on thymidine monophosphate synthesis. Expand
Evaluation of antibacterial activity of whey protein isolate coating incorporated with nisin, grape seed extract, malic acid, and EDTA on a Turkey frankfurter system.
It is demonstrated that the use of an edible film coating containing nisin, organic acids, and natural extracts is a promising means of controlling the growth and recontamination of L. monocytogenes, S. typhimurium, and E. coli O157:H7 in ready-to-eat poultry products. Expand