Evaluation of anti-inflammatory and chondroprotective effects of peroxisome proliferator-activated receptor gamma agonists in cartilage and synovial explants from dogs.

Abstract

OBJECTIVE To evaluate the effects of peroxisome proliferator-activated receptor gamma (PPARγ) agonists on tissue metabolism in cartilage and synovial explants from dogs. SAMPLE POPULATION Cartilage-synovial membrane expiants from 12 dogs. PROCEDURES Expiants were cultured for 21 days without (negative control) or with interleukin (IL)-1beta (positive… (More)
DOI: 10.2460/ajvr.71.10.1142

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