Evaluation of anti-inflammatory activity of Alstonia macrophylla Wall ex A. DC. leaf extract.

@article{Arunachalam2002EvaluationOA,
  title={Evaluation of anti-inflammatory activity of Alstonia macrophylla Wall ex A. DC. leaf extract.},
  author={Ganeshan Arunachalam and Dhrubajyoti Chattopadhyay and Soumyadeep Chatterjee and Asit Baran Mandal and Tapas Kumar Sur and Subhash C. Mandal},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2002},
  volume={9 7},
  pages={
          632-5
        }
}
Methanolic extract of dried leaves of Alstonia macrophylla Wall ex A. DC. and its fractions were investigated for its anti-inflammatory activity. The extract at a concentration of 200 mg kg(-1) and 400 mg kg(-1), p.o. and its fractions at 25 mg kg(-1) and 50 mg kg(-1), p.o. showed the significant dose dependent antiinflammatory activity in carrageenan and dextran-induced rats hind paw edema (acute models) as well as in cotton pellet-induced granuloma (chronic model) in rats. Anti-inflammatory… CONTINUE READING
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