Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay.

@article{Adcock2017EvaluationOA,
  title={Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay.},
  author={Robert S. Adcock and Yung-chiang Chu and Jennifer E Golden and Donghoon Chung},
  journal={Antiviral research},
  year={2017},
  volume={138},
  pages={
          47-56
        }
}
Recent studies have clearly underscored the association between Zika virus (ZIKV) and severe neurological diseases such as microcephaly and Guillain-Barre syndrome. Given the historical complacency surrounding this virus, however, no significant antiviral screenings have been performed to specifically target ZIKV. As a result, there is an urgent need for a validated screening method and strategy that is focused on highlighting potential anti-ZIKV inhibitors that can be further advanced via… CONTINUE READING
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