Evaluation of an ompA-based phage-mediated DNA vaccine against Chlamydia abortus in piglets.

@article{Ou2013EvaluationOA,
  title={Evaluation of an ompA-based phage-mediated DNA vaccine against Chlamydia abortus in piglets.},
  author={Changbo Ou and Deyu Tian and Yong Ling and Qing Pan and Qing He and Francis O. Eko and Cheng He},
  journal={International immunopharmacology},
  year={2013},
  volume={16 4},
  pages={505-10}
}
Chlamydia abortus (C. abortus) is an obligate intracellular pathogen that causes abortion in pigs and poses a zoonotic risk in pregnant women. Although attenuated and inactivated vaccines are available, they do not provide complete protection in animals underlining the need to develop new vaccines. In this study, we tested the hypothesis that intramuscular immunization with an ompA-based phage-mediated DNA chlamydial vaccine candidate will induce significant antigen-specific cellular and… CONTINUE READING
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