Evaluation of an assay for detecting telomerase activity in neoplastic tissues of dogs.

@article{Biller1998EvaluationOA,
  title={Evaluation of an assay for detecting telomerase activity in neoplastic tissues of dogs.},
  author={Barbara J Biller and Barbara E. Kitchell and Casey D Cadile},
  journal={American journal of veterinary research},
  year={1998},
  volume={59 12},
  pages={1526-9}
}
OBJECTIVE To determine feasibility of using the telomere repeat amplification protocol (TRAP) assay to detect telomerase activity in tumors of dogs. SAMPLE POPULATION Samples of tumor or normal tissue were obtained from client-owned dogs that underwent surgical biopsy during the period of January 1996 through December 1997. PROCEDURE The TRAP assay was used to detect telomerase activity in malignant or benign tumors of dogs. Telomerase status (positive or negative) was compared with results… CONTINUE READING