Evaluation of amino acids as mediators for the antibacterial activity of iodine-lithium-alpha-dextrin in vitro and in vivo.

@article{Davtyan2007EvaluationOA,
  title={Evaluation of amino acids as mediators for the antibacterial activity of iodine-lithium-alpha-dextrin in vitro and in vivo.},
  author={Tigran K. Davtyan and Isabelle S Hakobyan and Rafael Muradyan and Hrachya G Hovhannisyan and Emil S Gabrielyan},
  journal={The Journal of antimicrobial chemotherapy},
  year={2007},
  volume={59 6},
  pages={
          1114-22
        }
}
OBJECTIVES The systemic therapeutic application of iodophores has not yet been accepted due to limited availability of safe and effective ionized iodine preparations. Here we evaluated the antibacterial activity of iodine-lithium-alpha-dextrin (ILalphaD) both in vitro and in vivo. METHODS The MIC values of ILalphaD against 189 bacterial isolates in various growth media and in vivo toxicity and protective efficacy of ILalphaD in preventing mortality of rats infected with Staphylococcus aureus… 
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