Evaluation of adapted whole-blood interferon-gamma release assays for the diagnosis of pleural tuberculosis.

@article{Chegou2008EvaluationOA,
  title={Evaluation of adapted whole-blood interferon-gamma release assays for the diagnosis of pleural tuberculosis.},
  author={Novel N Chegou and Gerhard Walzl and Chris Thomas Bolliger and A. H. Diacon and Michel Maria van den Heuvel},
  journal={Respiration; international review of thoracic diseases},
  year={2008},
  volume={76 2},
  pages={131-8}
}
BACKGROUND Pleural tuberculosis (TB) remains difficult to diagnose despite numerous diagnostic tools. Recently, in vitro interferon (IFN)-gamma-based assays have been introduced in the diagnosis of latent TB, but these techniques have not been established in the diagnosis of active TB disease, including pleural TB. OBJECTIVES It was the aim of this study to assess the accuracy of the commercially available QuantiFERON TB Gold assay and adapted variants of the assay, using pleural fluid or… CONTINUE READING
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